I've purchased 6 5m reels of the #306 LDP8806 based digital RGB LEDs. The first 4 reels have worked great for a few months and are in continuous use,24x7. I've noticed no problems with them at all.
The last two reels, purchased in mid-March, worked great for a few days, then partially failed. Both were driven by the same 5volt power supply and controller (and custom PIC based controller) that was used to to "burn in" testing for the other 4 reels. After about 3 days of testing, the first reel stopped working at around the 10th LED and on the second reel, after about 6 days of testing, the reel stopped working somewhere around the middle of the LEDs.
All LEDs before the failed one continue to work fine. The LEDs were never unrolled from the reel, so were not subjected to any mechanical, electrical or EMF/EMI stress. The power supply is highly regulated (it's one from the Adafruit store -- the 5V, 10A unit).
I'm working with Adafruit to get these replaced. However, as I tend to use them for installations that are pretty-permanent (and difficult to service once in use), I'm trying to see if anyone else has had problems with strips failing lately. Such a case might suggest a "bad batch". My hope is it's just a bad batch. The alternative would be having to test each reel for weeks and expect up to a 33% failure rate over time.
So if anyone has run into any of these strips that later failed somewhere in the strip, I (and adafruit) would appreciate a brief addition/posting/comment about the wheres, hows and, ideally when you purchased the strip from adafruit.